Terminology
- Continuous positive airway pressure (CPAP) – the delivery of continuous level of positive airway pressure.
- Functionally similar to positive end expiratory pressure (PEEP), the ventilator does not cycle during CPAP
- No additional pressure above the level of CPAP is provided
- Patients must initiate all their own breaths.
- Most often used for obstructive sleep apnea.
- Bilevel positive airway pressure (BPAP/BiPAP)- bilevel positive airway pressure is a mode used during noninvasive positive pressure ventilation (NPPV).
- BPAP delivers a preset inspiratory positive airway pressure (IPAP) and expiratory positive airway pressure (EPAP)
- Tidal volume correlates with the difference between IPAP and EPAP.
- BPAP offers several advantages compared to CPAP.
- Notably it is an active ventilation rather than solely pneumatic splinting of the upper airway.
- A lower mean airway pressure (which means it is often tolerated better)
- Allows for rest of ventilator muscles
- Quicker resolution of respiratory acidosis
- However, it does have an issue with asynchrony
- Assist Control (A/C) – physician determines minimal minute ventilation by setting respiratory rate and tidal volume.
- Patient can trigger additional breaths, which are delivered with the same tidal volume as the previous breaths.
- Synchronized Increased Minute Ventilation (SIMV) –SIMV delivers a minimum number of fully assisted breaths per minute that are synchronized with the patient's respiratory effort
- These breaths are patient- or time-triggered, flow-limited, and volume-cycled.
- Any breaths taken between volume-cycled breaths are not assisted
- The volumes of these breaths are determined by the patient's strength, effort, and lung mechanics
- A key concept is that ventilator-assisted breaths are different than spontaneous breaths
- Another important concept is that AC and SIMV are identical modes in patients who are not spontaneously breathing due to heavy sedation or paralysis.
- SMV is seen as better because it increases patient work to preserve respiratory muscle function
- SIMV allows for better titration of ventilator support
- Volume control (VC) breaths are ventilator-initiated breaths with a set inspiratory flow rate.
- Inspiration is terminated once the set tidal volume has been delivered.
- Volume assist (VA) breaths are patient-initiated breaths with a set inspiratory flow rate.
- Inspiration is terminated once the set tidal volume has been delivered.
- Pressure control (PC) breaths are ventilator-initiated breaths with a pressure limit.
- Inspiration is terminated once the set inspiratory time has elapsed.
- The tidal volume is variable and related to compliance, airway resistance, and tubing resistance.
- A consequence of the variable tidal volume is that a specific minute ventilation cannot be guaranteed.
- Pressure support (PS) breaths are patient-initiated breaths with a pressure limit.
- The ventilator provides the driving pressure for each breath, which determines the maximal airflow rate.
- Inspiration is terminated once the inspiratory flow has decreased to a predetermined percentage of its maximal value.
- Extrinsic positive end-expiratory pressure (Applied PEEP) is generally added to mitigate end-expiratory alveolar collapse.
- A typical initial applied PEEP is 5 cm H2O, and this is adjusted accordingly depending on if atelectasis persists.
- Flow rate — The peak flow rate is the maximum flow delivered by the ventilator during inspiration.
- The need for a high peak flow rate is particularly common among patients who have obstructive airways disease with acute respiratory acidosis.
- In such patients, a higher peak flow rate shortens inspiratory time and increases expiratory time (ie, decreases the inspiratory to expiratory [I:E] ratio).
- These alterations:
- Increase carbon dioxide elimination
- Improve respiratory acidosis
- Decrease the likelihood of dynamic hyperinflation (auto-PEEP)
- End Tidal CO2 (Capnography)- provides instantaneous information about:
- Ventilation (how effectively CO2 is being eliminated by the pulmonary system)
- Perfusion (how effectively CO2 is being transported through the vascular system)
- Metabolism (how effectively CO2 is being produced by cellular metabolism)
- Used frequently in kids with vents as an easy way of assessing ventilation status.
- Can be used to trend acid/base states, especially in conjunction with VBGs.
- Capnography can be useful in evaluating respiratory status and is much quicker than pulse oximetry.
- Make sure to look at wave forms to make sure that ETCO2 readings are accurate (look for a smooth hump) or else capnography readings may be abnormally high or low due to physiologic dead space.
http://clinicalgate.com/confirmation-of-endotracheal-intubation/
The CO2 waveform: A, Expiratory pause begins; A–B, Clearance of anatomic dead space; B–C, Dead space air mixed with alveolar air; C–D, Alveolar plateau; D, End-tidal partial pressure of CO2 registered by capnograph (arrow) and beginning of inspiratory phase; D–E, Clearance of dead space air; E–A, Inspiratory gas devoid of CO2.
- Chest Physiotherapy (CPT)- involves hyperoxygenation by bagging (or vent) with 100% oxygen, deep endotracheal instillation of 0.25-0.5ml/kg sterile saline, bagging with momentary inspiratory hold, followed by release of the hold and simultaneous forced exhalation and vibration to stimulate cough, and endotracheal suctioning.
- Commonly done in children with persistent atelectasis or cystic fibrosis
- Cough Assist – patients with respiratory muscle weakness can’t generate the force necessary to produce an effective cough.
- Mechanical insufflation-exsufflation can be delivered via mechanical device to patients who are spontaneously breathing or mechanically ventilated (works best in patients with trachs).
- Positive pressure is applied during inhalation, and rapid exsufflation quickly follows generating a negative pressure differential which leads to a simulated cough.
Jim Beck, MD, Division of Pulmonary and Critical Care Medicine, University of Michigan
References
- Mechanical Ventilation: Basic Review, University of Colorado School of Medicine, Department of Internal Medicine http://www.ucdenver.edu/academics/colleges/medicalschool/departments/medicine/intmed/imrp/CURRICULUM/Documents/Mechanical%20ventilation%20review.pdf
- Ventilator Management, Medscape, 2015 http://emedicine.medscape.com/article/810126-overview
- Management and Prognosis of patients requiring prolonged mechanical ventilation, Up To Date, 2015http://www.uptodate.com/contents/management-and-prognosis-of-patients-requiring-prolonged-mechanical-ventilation?source=search_result&search=ventilator+management&selectedTitle=3%7E150
- Overview of Mechanical Ventilation, Up To Date, 2015
- http://www.uptodate.com.proxy.uchicago.edu/contents/overview-of-mechanical-ventilation?source=search_result&search=mechanical+ventilation&selectedTitle=1%7E150
- Critical Care Medicine Tutorials : http://www.ccmtutorials.com/rs/mv/